Enhancement of bioelectrochemical dioxygen reduction with oxygen-enriching materials

Bioelectrochemical dioxygen reduction reaction (ORR) catalyzed by multi-copper oxidases (MCOs) is a process of paramount importance occurring at the cathode enzymatic biofuel cells (EBFCs), which an energy harvester that holds promise self-sustained implantable and wearable medical devices. The MCO biocathode is, however, frequently limiting factor working EBFC. Besides operational stability issue, biocathodes are largely constrained relatively low solubility in aqueous solution. As emerging topic, we here review introduction dioxygen-enriching materials to cathodic bioelectrode for overcoming supply limitation, leading improved ORR performance.